Posts tagged ‘lung cancer’


AACR 2014: Thwarting drug-resistant lung cancer with a novel compound

April 4, 2014 | by
lung cancer
Despite advances made in detecting and treating nonsmall cell lung cancer, its prognosis remains grim. Even patients whose cancers are caught at their earliest stage have only a 50 percent chance of five-year survival. This poor prognosis is due in part to the cancer’s ability to resist treatment, rendering the chemotherapy ineffective. A novel compound synthesized at City of Hope can target and treat drug-resistant lung cancers, researchers find. However, a group of City of Hope researchers have identified and synthesized a novel compound — called COH-SR4 — that is effective against drug-resistant lung cancer. If…

New options needed, and likely, for ALK-positive lung cancer

March 30, 2014 | by
lung cancer
People with what’s known as ALK-positive lung cancer usually develop resistance to crizotinib, the primary drug used to treat their disease. The drug’s limitations are all the more significant because its approval in 2011 was considered a crucial advance against this type of nonsmall cell lung cancer. People with ALK-positive nonsmall cell lung cancer may have new drug options in the not-too-distant future. Those options are desperately needed. “This makes new therapies for ALK-positive lung cancer essential to improving and prolonging life for these patients,” said Karen L. Reckamp, M.D. , M.S., co-director of City of Hope’s…

Lung cancer patient highlights need for survivor research (VIDEO)

March 12, 2014 | by
lung cancer
“Susan survived breast cancer 20 years ago.” So begins a video of a former City of Hope patient sharing the story of her lung cancer diagnosis and her subsequent treatment at City of Hope. In her narrative, the former patient expresses shock at her diagnosis, saying she was “totally floored.” After all, she’d never smoked, and the common perception of lung cancer has been that it’s a disease only of smokers. That perception is slowly changing. As explained by Karen Reckamp, M.D., M.S., co-director of City of Hope’s Lung Cancer and Thoracic Oncology Program: “The most…

Cancer of the breast, colon, lungs … Putting research in perspective

March 3, 2014 | by
Commentary on cancer research
No matter how impressive a research study’s conclusion may be – or how seemingly unsurprising – experts are needed to put the findings into context. Perhaps a study’s methodology wasn’t as strong as it could have been. Perhaps the conclusions confirmed that other researchers are on the right track. Perhaps the study missed the mark completely. City of Hope physicians offer context and insight on recent cancer research. City of Hope’s physicians recently weighed in on an array of recent published studies, offering their expertise, insight and perspective via a special commentary feature in Clinical Oncology…

What’s in cigarette smoke? Name your poison

February 14, 2014 | by
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Cigarettes are obviously bad for your health. They’re blamed for one in five deaths in the United States and for 90 percent of lung cancer deaths, according to the Centers for Disease Control and Prevention. They also contribute to the risk heart disease, aneurysms, bronchitis, emphysema and stroke. In fact, cigarettes cause more deaths each year than HIV, illegal drug use, alcohol use, car accidents and guns –  combined. Most people understand that cigarettes contain chemicals. What they might not understand is what happens when those chemicals are burned. Once lit, a cigarette releases – via smoke…

This February, aka Heart Month, learn what smoking does to your heart

February 1, 2014 | by
Heart disease and cigarettes
February may be popularly known as the month of love, but it also holds the title of American Heart Month, aiding as a reminder to take care of your heart. One way is to quit smoking. Take care of your heart by giving up cigarettes. It will lower your risk of heart disease. Not only do cigarettes cause 30 percent of all cancer deaths in the United States, they also contribute to America’s biggest killer: heart disease. Nearly 600,000 people die of heart disease in the United States every year, with almost 20 percent of those…

Don’t wait for a doctor to suggest lung cancer screening

January 24, 2014 | by
lung cancer
Nearly 160,000 Americans die of lung cancer each year. New lung cancer screening recommendations from the U.S. Preventive Services Task Force mean that most insurance plans will begin covering the screening within a year. New lung cancer screening guidelines recommended by the U.S. Preventive Services Task Force in the last month could make a considerable dent in that number. The panel, which determines what therapies and tests must be covered by insurers under the Affordable Care Act, made final its July recommendation that current and former smokers between 55 and 80 years old who have…

50 years of tobacco control: Impact measured in lives saved

January 20, 2014 | by
This month marks 50 years of tobacco control efforts, which have reaped rewards in lives saved.
From warning labels to taxes to banning advertising, the U.S. has taken serious steps over the past 50 years to diminish the effects of tobacco on American health. This month marks 50 years of tobacco control efforts, which have reaped rewards in lives saved. The surgeon general took the first step 50 years ago this month, issuing a report based on 7,000 scientific articles and concluding that smoking causes lung cancer and other lung disease. Between the powerfully addictive nature of cigarettes and other tobacco products and the economic forces promoting them, the battle against…

New Year’s resolutions: Tips on how to quit smoking

December 30, 2013 | by
Smoking Tips
Quitting smoking may be hard, but it’s not impossible. City of Hope smoking-cessation experts offer tips on how to kick the habit for good. The new year is fast approaching, and with nearly 70 percent of adult smokers wanting to kick the habit, many people are likely to make the resolution to give up cigarettes for good in 2014. That’s great — tobacco is the leading cause of preventable illness and death in the United States and over half of smokers reaching middle age will die of a smoking-related illness. Further, it’s never too late to quit. Quitting smoking…

Cancer treatment in 2014: Making the most of research

December 29, 2013 | by
Fighting cancer
Cancer will be defeated not in one enormous advance, experts agree, but in incremental advances. Those incremental advances often go unnoticed by the public at the time of their discovery, but in the years to come, they add up – to more life years, to greater survival rates, to more time spent with families and loved ones. In 2014, patients will begin to see the benefits of many of those advances. Here, City of Hope’s physicians describe some of the recent scientific and medical developments they expect to benefit patients in the year ahead. Breast cancer: A…