Posts tagged ‘leukemia’


Meet our doctors: Hematologist Leslie Popplewell on clinical trials

March 2, 2014 | by
Clinical trials
Research studies known as clinical trials have led to countless advances in the diagnosis, treatment and prevention of cancer. These studies test the effectiveness of new medical approaches that can lead to fewer treatment-related side effects and, in some cases, improved outcomes for patients with certain cancers. Leslie Popplewell says clinical trials can offer additional treatment options for patients. But many patients know little about clinical trials, much less what’s involved to participate. Here,  Leslie Popplewell, associate professor in the Department of Hematology & Hematopoietic Cell Transplantation at City of Hope, explains how clinical trials work and…

New CMV vaccine targets virus affecting third of transplant patients

February 3, 2014 | by
Vaccine expert John Zaia
In most healthy adults, the immune system wages a winning battle against a virus that infects up to 80 percent of the population by age 40. Most never even know they have cytomegalovirus, or CMV. John Zaia, chair of the Department of Virology, checks on Jasson Duran, the first volunteer enrolled in a study of a new CMV vaccine developed and manufactured at City of Hope. However, the virus is a leading cause of complications and serious illness in patients who have compromised immune systems, including those receiving hematopoietic cell transplants to treat leukemia or lymphoma. CMV…

‘My cancer diagnosis: What I wish I’d known’ – Bishop J. Jon Bruno

December 23, 2013 | by
COH
Bishop J. Jon Bruno will be one of 11 former City of Hope patients riding atop our float on New Year’s Day. Read other riders’ stories and learn more about the float, “Turning Hope and Dreams into Reality.” ** The larger-than-life J. Jon Bruno, bishop of the six-county Los Angeles Episcopal Diocese, oversees 147 parishes and missions, 44 schools, and 20 institutions. He’s the father of three and the grandfather of seven. He was a professional football player and police officer before becoming an Episcopal priest then a bishop. Bishop J. Jon Bruno of the L.A. Episcopal Diocese,…

Exploring cognitive decline after hematopoietic cell transplant

December 17, 2013 | by
Illustration of the human brain
Hematopoietic cell transplant patients who undergo what’s known as myeloablative conditioning (that is, high-intensity chemotherapy and radiation) – and who have shorter telomeres (chromosome “end caps”) – may be at greater risk for cognitive impairment after transplant, City of Hope researchers have found. Their study was presented earlier this month at the American Society of Hematology (ASH) Annual Meeting and Exposition in New Orleans in December. “Our goal was to understand the trajectory of their cognitive functioning after transplantation and also if there are some vulnerable subpopulations at increased risk of cognitive impairment,” said senior author Smita Bhatia, M.D., M.P.H.,…

Leukemia diagnosis made Bishop J. Jon Bruno see his true impact

December 16, 2013 | by
COH
Bishop J. Jon Bruno will be one of 11 former City of Hope patients riding atop our float on New Year’s Day. Read other riders’ stories and learn more about the float, “Turning Hope and Dreams into Reality.” ** After returning home from cancer treatment at City of Hope in May 2012, J. Jon Bruno was astonished to see his Pasadena, Calif., family room crowded with mail bags filled with more than 25,000 handwritten letters. “I read every one of them,” said 67-year-old Bruno, bishop of the six-county Los Angeles Episcopal Diocese. Bishop J. Jon Bruno…

Why a secondary cancer after transplant? Grant may help find clues

December 11, 2013 | by
DNA analysis
Myelodysplastic syndrome, once known as “preleukemia,” is a disease of the blood and bone marrow that often attacks people who have survived initial cancer treatment. “Good Morning America” co-host Robin Roberts, for example, was diagnosed with the syndrome, known as MDS, in June 2012, five years after successfully undergoing treatment for breast cancer. She’s one of an estimated 12,000 Americans who are diagnosed with the syndrome each year. Smita Bhatia and Ravia Bhatia, researchers at City of Hope, have received a grant from the V Foundation for Cancer Research to study MDS. They’ll be using genomic tools to analyze mutations…

Jaylon Fong is a Sports Illustrated Kids ‘Sportskid of the Year’

December 10, 2013 | by
COH
Five years ago this month, Jaylon Fong was diagnosed with leukemia. He underwent chemotherapy and a rigorous treatment plan before going into remission. But that proved to be only his first battle with the disease. He was rediagnosed in 2012 and suffered a central nervous system relapse. Today, he is a two-time cancer survivor – at age 13. Jaylon Fong is featured in the December 2013 issue of Sports Illustrated Kids. Photo credit: Kohjiro Kinno for Sports Illustrated. Jaylon’s courage and perseverance, especially at such a young age, have been inspiring. He has endured procedures, infusions and…

Rose Parade float: John Cloer – healthy at 12 and inspiring

December 5, 2013 | by
John Cloer shares his new smile. Photo credit: Cloer family
John Cloer shares his new smile. Photo credit: Cloer family For those who have battled cancer, each tomorrow is, in reality, a dream come true. On Jan. 1,  former City of Hope patients will see another dream come true: They’ll be riding atop City of Hope’s float in the 2014 Tournament of Roses Parade. The theme of this year’s float is “Turning Hope and Dreams into Reality”; the theme of the parade is “Dreams Come True.” Here is the story of one rider: John Cloer. ADD YOUR WISH WITH A GIFT »   ** My name is John…

Meet our doctors: Julie Wolfson on cancer in teens, young adults

November 16, 2013 | by
Julie Wolfson
Adolescents and young adults (AYAs) with cancer have different needs and treatment challenges than children or older adults. They’re a unique population because they don’t fit into a distinct group, often falling into a gap between cancer treatment programs designed for children and those designed for adults. City of Hope pediatric oncologist Julie Wolfson Here, pediatric oncologist Julie Wolfson, M.D., M.S.H.S., discusses how the cancer experience differs for AYAs and how City of Hope’s multidisciplinary AYA team offers assistance and a network of professionals to support teens and young adults from the beginning of treatment through…

Stem cell transplants can take toll on sexual health, study finds

November 4, 2013 | by
sexual health
Blood and bone marrow stem cell transplants can be lifesaving procedures for patients with blood cancers such as leukemia, lymphoma and myeloma. But they can take a heavy physical and emotional toll. Preparations for stem cell transplants and complications associated with the procedure lead to can diminished sexual health for both men and women, researchers found. City of Hope researchers have long been concerned about the effect of stem cell transplants on patients’ overall quality of life, and they recently focused their attention on one specific aspect — patients’ sexual well-being. What they found was sobering.…