Posts tagged ‘City of Hope’
Brain tumor removal would seem to be the obvious course of action in the wake of a brain tumor diagnosis, but that’s not always the case. Some tumors are too difficult for many surgeons to reach or too close to areas that control vital functions. Removing them just proves too risky.
A new device at City of Hope, however, allows neurosurgeons to not only reach these tumors safely, but to remove them in a carefully controlled way. This device, called the NeuroBlate, is an MRI-guided laser that destroys tumors through ablation, avoiding both traditional surgery and a craniotomy; that is, the removal of part of the skull.
“Ablation, or directing energy to kill tumor tissue is not a new thing,” said Mike Chen, M.D., Ph.D., assistant professor, Division of Neurosurgery at City of Hope. “The difference with NeuroBlate, or the newest generation of ablations systems, is that they are designed to be inserted stereotactically.” Stereotactic surgery uses very small incisions and extremely precise, three-dimensional positioning. » Continue Reading
With Labor Day just around the corner, summer is on its way out. But just because summertime is ending doesn’t mean we can skip sunscreen. Protection from ultraviolet (UV) radiation is needed all year round. Exposure to UV radiation — whether from the sun or from artificial sources such as sunlamps used in tanning beds — increases the risk of melanoma, the deadliest form of skin cancer.
Here, Jae Jung, M.D., Ph.D., assistant professor in dermatology at City of Hope, shares simple prevention tips to lower the risk of melanoma. She also explains that the disease is almost always curable if detected and treated in its earliest stages.
What is melanoma and what causes it?
Melanoma is a type of skin cancer. It arises from melanocytes, the cells that produce pigment in our skin. They are most common in sun-exposed areas of the skin, but can arise anywhere including under the fingernails, oral or genital mucosa, and eyes.
Melanoma is usually caused by too much UV exposure, either from natural sun or in tanning booths. Use of tanning beds can increase your risk of melanoma by 75 percent. Patients with fair skin, light hair and eyes, have a propensity to sunburn and are at higher risk of developing melanoma. Patients with many moles (greater than 50), atypical moles, and a family history of melanoma are also at increased risk. » Continue Reading
Christine Crews isn’t only a fitness enthusiast, she’s also a personal trainer and fitness instructor. Being active defines her life. So when she was diagnosed with bladder cancer at age 30, she decided she absolutely couldn’t let the disease interfere with that lifestyle.
And it didn’t. For the next 15 years, Crews continued to run marathons, teach fitness classes and train 20 to 30 clients a week, all while fighting her bladder cancer with chemotherapy and periodic tumor removals.
Thanks to the California Institute for Regenerative Medicine (CIRM), high school students across the state gained valuable hands-on experience with stem cell research this summer. City of Hope hosted eight of those students.
As part of the CIRM Creativity Awards program, the young scholars worked full time as members of our biomedical research teams. They received mentoring from physicians and scientists and interacted closely with each other and their mentors to gain firsthand practice in laboratory research with stem cells.
Through the Creativity Awards, CIRM supported students at nine institutions throughout the state. Students were encouraged to share their experiences through various social media outlets with videos, blog posts and Instagram photos.
The video, produced by student interns here at City of Hope, was named a favorite by CIRM and gained widespread attention from news media outlets including NBC4 Los Angeles, the Bay Area’s ABC7 and NBC4 in New York. Drawing from the hit movie “Frozen,” the video encourages stem cells (and presumably the students) to — you guessed it — “Let It Grow.”
Take a look, and join us in congratulating these creative young scientists.
Radiation therapy can help cure many children facing Hodgkin lymphoma and other cancers. When the radiation is delivered to a girl’s chest, however, it can lead to a marked increase in breast cancer risk later in life.
A recent multi-institutional study that included City of Hope’s Smita Bhatia, M.D., M.P.H., the Ruth Ziegler Chair in Population Sciences, examined the long-term effects of chest radiation on female survivors of childhood cancers, primarily Hodgkin lymphoma. The researchers wanted to determine whether more current therapies using less radiation could reduce the breast cancer risk, and if the amount of area exposed was a factor.
Past research has shown that standard doses of radiation therapy to the chest increase breast cancer risk, with incidence rates among these women ranging from 5 percent to 14 percent by age 40.
For the current chest radiation study, lead author Chaya Moskowitz, Ph.D., of Memorial Sloan Kettering Cancer Center in New York, and the research team looked at more than 1,200 women who received various amounts of radiation in treatment of childhood cancers. They found that even women who received lower amounts of radiation as children still were much more likely to develop breast cancer than the average woman, with as many as 30 percent developing breast cancer by age 50. » Continue Reading
A patient diagnosed with cancer – especially a rare, advanced or hard-to-treat cancer – needs specialized care from exceptionally skilled and highly trained experts. That kind of care saves lives, improves quality of life and keeps families whole.
That kind of care is best found at comprehensive cancer centers like City of Hope.
One of the top cancer hospitals for cancer in the United States, according to U.S.News & World Report’s annual rankings, City of Hope has also been awarded the highest level of accreditation from the American College of Surgeons Commission on Cancer and is listed on Becker’s Hospital Review’s 2014 list of “100 Hospitals and Health Systems With Great Oncology Programs.”
Further, recent research found that receiving cancer care at a comprehensive cancer center improves survival of patients with cancers of the breast, lung, liver, stomach, pancreas and oral tissues, among others.
The cancer patients in the video above don’t need to be convinced by such commendations or research, however. They were convinced by City of Hope itself.
Read more about them:
- Sheldon Querido: bladder cancer
- Bridget Hanchette: glioblastoma
- Christine Pechera: lymphoma
- Charlie Habib: dermatofibrosarcoma
Learn more about becoming a patient or getting a second opinion at City of Hope by visiting us online or by calling 800-826-HOPE (4673). City of Hope staff will explain what’s required for a consult at City of Hope and help you determine, before you come in, whether or not your insurance will pay for the appointment.
Stevee Rowe has a very personal connection to the research she’s conducting on neural stem cells: Her late father participated in a City of Hope clinical trial involving neural stem cells.
Rowe — her full name is Alissa Stevee Rowe, but she prefers to use her middle name — will enter her senior year at the University of California, Riverside, this fall. She currently is enrolled in the Eugene and Ruth Roberts Summer Student Academy. Her project examines neural stem cells used to target brain cancer.
Her father, Steven Keith Rowe, was a patient at City of Hope who enrolled in a clinical trial to treat his brain tumor with neural stem cells. “My father wanted to help further research and was always willing to try anything he could,” she said. Now she hopes to do the same. » Continue Reading
Some proteins really know how to multitask. Some of the best are called G-protein coupled receptors, or GPCRs, for short.
New research by City of Hope scientists Nagarajan Vaidehi, Ph.D., and Supriyo Bhattacharya, Ph.D., shows how a single GPCR can have very different effects in a cell depending on the molecule that stimulates it. The scientists’ findings could help researchers create better targeted drugs with fewer side effects.
A protein supergroup
GPCRs comprise a superfamily of proteins involved in a wide range of biological processes including immunity, maintaining blood pressure, nerve cell activity and even cancer growth and spread. » Continue Reading
Skin cancer rates have been on the rise for years. On Tuesday, the U.S. surgeon general said: Enough.
In issuing the first-ever Call to Action to Prevent Skin Cancer, acting Surgeon General Boris Lushniak described skin cancer as a “major public health problem” that requires action by all segments of society.
Nearly 5 million people in the United States are treated for skin cancer each year, the report said, making it the most commonly diagnosed cancer in the United States, with annual treatment costs reaching an estimated $8.1 billion. It’s also one of the most preventable cancers.
Everyone has a role to play in the skin cancer prevention effort, Lushniak stressed, saying that governments across the board (not just federal and state, but also tribal, local and territorial) need to be partners with business, health care and education leaders; community, nonprofit and faith-based organizations; and of course individuals and families.
He’ll find little argument from skin cancer experts, including City of Hope dermatologist Jae Jung, M.D., Ph.D. She’s seen the profound impact of skin cancer on society and the alarming rise in skin cancer rates among young people. » Continue Reading