Blueberries, cinnamon, baikal scullcap, grape seed extract (and grape skin extract), mushrooms, barberry, pomegranates … all contain compounds with the potential to treat, or prevent, cancer.
Scientists at City of Hope have found tantalizing evidence of this potential and are determined to explore it to the fullest. They’re researching, testing and developing new therapies made from nature’s bounty — from the vegetables, fruits and herbs many people take for granted as simply plants, not medicine.
To help them in their work, City of Hope has launched a Program in Natural Therapies, an effort to find more effective, but also less toxic, cancer therapies. The researchers have already made considerable progress. » Continue Reading
In a single day, former professional triathlete Lisa Birk learned she couldn’t have children and that she had breast cancer.
“Where do you go from there?” she asks.
For Birk, who swims three miles, runs 10 miles and cycles every day, the answer ultimately was a decision to take control of her cancer care. After receiving less-than-ideal treatment at a local hospital, Birk came to City of Hope.
Having cancer didn’t change her exercise routine, and it wasn’t going to change her ability to manage her life.
Learn more about her story – and why expert cancer care matters – in this video.
Learn more about breast cancer treatment and research at City of Hope.
Learn more about becoming a patient or getting a second opinion by visiting our website or by calling 800-826-HOPE (4673). City of Hope staff will explain what’s required for a consult at City of Hope and help you determine, before you come in, whether or not your insurance will pay for the appointment.
Jonathan Yamzon, M.D., assistant clinical professor of surgery in the Division of Urology and Urologic Oncology, explains his approach to what’s known as “active surveillance” of men with prostate cancer. Patients need to be educated about their treatment options, he writes.
Active surveillance eligibility
Active surveillance is an option offered to patients with “low-risk” prostate cancer. It entails forgoing any immediate treatment, and instead monitoring a patient’s cancer to ensure it shows no signs of worsening. If there are any signs of disease progression, the option for curative treatment can still be offered. Active surveillance attempts to avoid unnecessary treatments for patients with prostate cancers that may not become clinically significant or impactful to a man’s life.
Such treatments have potential risks for side effects. Those considered low-risk have a prostate specific antigen (PSA) value of less than 10, a biopsy Gleason of six or less, and a rectal exam that reveals nothing beyond a small nodule confined to one side of the prostate. When one of my patients embarks on active surveillance, I repeat the PSA, rectal exam and biopsy to ensure that their tumor is in fact truly low-risk. The success of this strategy is predicated on recurring follow-ups and reassessment to detect worsening changes of the tumor grade, volume or stage. It is important to understand that if there are signs of cancer progression, we can still offer treatment with curative intent.
Currently, our ability to stratify who is low-risk is based on clinical parameters of the PSA, Gleason score and clinical stage, which is detected by a rectal exam. Newer biomarkers are being studied to improve risk stratification, including the use of novel markers in serum, urine, biopsy tissue and radiographic test like magnetic resonance imaging (MRI).
Radiation oncology is one of the three main specialties involved in the successful treatment of cancer, along with surgical oncology and medical oncology. Experts in this field, known as radiation oncologists, advise patients as to whether radiation therapy will be useful for their cancer – and how it can best be safely and effectively delivered.
Here, Jeffrey Y.C. Wong, M.D., chair of radiation oncology at City of Hope, shares what he sees as the future of radiation oncology and the importance of this type of therapy in the treatment of cancer.
How and why did you decide to become a radiation oncologist?
I’ve always had an interest in the math, physics and engineering fields. I almost became an engineer, but decided to switch to oncology with a focus in medicine, and radiation oncology is a good blend of both. Radiation oncology is a blend of engineering, computer sciences, physics, biology and medicine, with the primary goal of helping people.
What inspires you daily to do the work you do?
I, along with my colleagues at City of Hope, have the opportunity to make a difference in patients” lives every day. For many patients, our therapies can help result in a cure of their cancer. We also have the opportunity to make a contribution to cancer research and advance the field of oncology. » Continue Reading
September is Prostate Cancer Awareness Month. Here, Bertram Yuh, M.D., assistant clinical professor in the Division of Urology and Urologic Oncology at City of Hope, explains the importance of understanding the risk factors for the disease and ways to reduce those risks, as well as overall prostate health.
“What are my prostate cancer risks?” That’s becoming a more common, and increasingly important, question.
A lot of men wonder what can be done to prevent or reduce their risk of prostate cancer. The good news is, there’s a lot of research being conducted in this area regarding risks and influencing factors.
We already know there are racial predilections, such as that African-American men are more likely to get prostate cancer and that, when they’re diagnosed, the cancer tends to be more aggressive. We also know that prostate cancer is less common in Asian-American and Hispanic men.
Further, while prostate cancer is certainly more common in older men, there is some recent clinical literature that states prostate cancer in younger men can be more aggressive. It is quite possible for a 47-year-old and a 77-year-old to have prostate cancers that behave differently.
I can’t treat every patient the same way just because their prostate-specific antigen (PSA) or Gleason grades look the same. In my role as a urology oncologist, I need to look at the whole patient.
Learn more about getting a second opinion at City of Hope by visiting us online or by calling 800-826-HOPE (4673). City of Hope staff will explain what’s required for a consult at City of Hope and help you determine, before you come in, whether or not your insurance will pay for the appointment.
Jennifer Linehan, M.D., an assistant clinical professor in City of Hope’s Division of Urology and Urologic Oncology in Antelope Valley, thought she knew all there was to know about treating prostate cancer. Then her father was diagnosed with the disease. This is her story.
My father is 69 years old, has no health problems, is very active and still works diligently every day, from 5 a.m. till the evening. He is always smiling, laughing and enjoying life no matter what comes his way. He is an inspiration to me.
About 12 months ago, I was waiting for him to send me his prostate specific antigen (PSA) results from his recent physical. I just wanted to take a look. He was busy at work and told me that his PSA number was fine. I asked my mom to email it to me anyway. His PSA score was 28. I was stunned. I re-read the number at least twice to make sure it didn’t read 2.8 instead of 28.
How could this be? I am a urologist. How did I miss this? My head spun as every worst-case scenario started to fill my mind. As I was trying to calm down, I realized he needed a prostate biopsy. I started to think about who would do his surgery. He needed to come to City of Hope. My thoughts were racing. I began to wonder how far the disease had spread.
Finally, I got the nerve to call my parents; they could hear that my voice was panicked. I was panicked. I knew the realities that came with a high PSA and being diagnosed with prostate cancer. I was trying to keep calm, but instead blurted out: “How did this happen? Hasn’t your primary care physician been checking?”
Apparently, my father had been given the option of having his PSA checked for the last five years, but he refused every time. He told me that it was easier not knowing and not getting checked, because he was feeling fine. I tried to explain to him that prostate cancer is a silent killer. Often, a man won’t have any symptoms until the disease has progressed into the spine. I took a deep breath, apologized for my overreaction, and walked my parents through the next steps.
I was supposed to be the calm one, in control, but it’s all so different when someone so close to you is diagnosed.
Christine Crews isn’t only a fitness enthusiast, she’s also a personal trainer and fitness instructor. Being active defines her life. So when she was diagnosed with bladder cancer at age 30, she decided she absolutely couldn’t let the disease interfere with that lifestyle.
And it didn’t. For the next 15 years, Crews continued to run marathons, teach fitness classes and train 20 to 30 clients a week, all while fighting her bladder cancer with chemotherapy and periodic tumor removals.
Thanks to the California Institute for Regenerative Medicine (CIRM), high school students across the state gained valuable hands-on experience with stem cell research this summer. City of Hope hosted eight of those students.
As part of the CIRM Creativity Awards program, the young scholars worked full time as members of our biomedical research teams. They received mentoring from physicians and scientists and interacted closely with each other and their mentors to gain firsthand practice in laboratory research with stem cells.
Through the Creativity Awards, CIRM supported students at nine institutions throughout the state. Students were encouraged to share their experiences through various social media outlets with videos, blog posts and Instagram photos.
The video, produced by student interns here at City of Hope, was named a favorite by CIRM and gained widespread attention from news media outlets including NBC4 Los Angeles, the Bay Area’s ABC7 and NBC4 in New York. Drawing from the hit movie “Frozen,” the video encourages stem cells (and presumably the students) to — you guessed it — “Let It Grow.”
Take a look, and join us in congratulating these creative young scientists.
A patient diagnosed with cancer – especially a rare, advanced or hard-to-treat cancer – needs specialized care from exceptionally skilled and highly trained experts. That kind of care saves lives, improves quality of life and keeps families whole.
That kind of care is best found at comprehensive cancer centers like City of Hope.
One of the top cancer hospitals for cancer in the United States, according to U.S.News & World Report’s annual rankings, City of Hope has also been awarded the highest level of accreditation from the American College of Surgeons Commission on Cancer and is listed on Becker’s Hospital Review’s 2014 list of “100 Hospitals and Health Systems With Great Oncology Programs.”
Further, recent research found that receiving cancer care at a comprehensive cancer center improves survival of patients with cancers of the breast, lung, liver, stomach, pancreas and oral tissues, among others.
The cancer patients in the video above don’t need to be convinced by such commendations or research, however. They were convinced by City of Hope itself.
Read more about them:
- Sheldon Querido: bladder cancer
- Bridget Hanchette: glioblastoma
- Christine Pechera: lymphoma
- Charlie Habib: dermatofibrosarcoma
Learn more about becoming a patient or getting a second opinion at City of Hope by visiting us online or by calling 800-826-HOPE (4673). City of Hope staff will explain what’s required for a consult at City of Hope and help you determine, before you come in, whether or not your insurance will pay for the appointment.